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產(chǎn)品貨號(hào)Reference:             CAN-C-7010
檢測方法Kit Type:                Competitive LIA
規(guī)格Kit Size:                        96-well break-apart microplate
靈敏度Sensitivity:                0.15 μg/dL
檢測樣本Sample Type:        Human serum / 50 μL
檢測范圍Calibrator Range: 0.5–60 μg/dL
檢測時(shí)間Total Assay Time: 90 minutes
背景介紹：
皮質(zhì)醇是最豐富的循環(huán)類固醇，也是腎上腺皮質(zhì)分泌的主要糖皮質(zhì)激素。皮質(zhì)醇是生理上有效的血壓維持和抗?炎癥活動(dòng)。它還參與鈣的吸收、糖異生以及胃酸和胃蛋白酶的分泌。
血皮質(zhì)醇水平的測定可作為腎上腺功能的指標(biāo)，對(duì)阿狄森氏病、庫欣病、腎上腺增生及癌的鑒別診斷具有重要意義。
大多數(shù)循環(huán)中的皮質(zhì)醇與皮質(zhì)醇結(jié)合球蛋白或反式皮質(zhì)醇結(jié)合。因此，尿液中游離皮質(zhì)醇的濃度很低，24小時(shí)的尿液采集是獲得準(zhǔn)確測定尿皮質(zhì)醇的必要條件。血液中的皮質(zhì)醇呈晝夜節(jié)律，早晨含量最高，夜間含量最低。
Cortisol is the most abundant circulating steroid and the major glucocorticoid secreted by the adrenal cortex. Cortisol is physiologically effective in blood pressure maintenance and anti-in? ammatory activity. It is also involved in calcium absorption, gluconeogenesis as well as the secretion of gastric acid and pepsin. Measurement of blood cortisol levels can be used as an indicator of adrenal function and the differential diagnosis of Addison’s and Cushing’s diseases as well as adrenal hyperplasia and carcinoma.  Most circulating cortisol is bound to cortisol binding globulin or transcortin. Therefore, the free cortisol concentration excreted in the urine is very small, and the 24-hour collection of urine is a must in order to obtain an accurate measurement of urinary cortisol. Cortisol in blood shows a diurnal rhythm with the highest levels in the morning and the lowest levels at night.

注：本產(chǎn)品僅用于科研用途，不能直接用于人體或臨床診斷使用。