尾型同源盒轉(zhuǎn)錄因子2抗體/CDX-2 Antibody |
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產(chǎn)品名稱 : 尾型同源盒轉(zhuǎn)錄因子2抗體/CDX-2 Antibody
產(chǎn)品類別 : IVD診斷抗體原料
品 牌 : GenomeMe
貨 號 : IHC402
規(guī) 格 : 0.1ml/1ml
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純化方式 :
緩 沖 液 :
應(yīng)用說明 :
形 態(tài) :
產(chǎn)品說明 :
背景描述Description:
CDX-2是腸上皮細胞表達的一種與尾相關(guān)的同源盒轉(zhuǎn)錄因子。CDX-2是一種有用的胃腸道腫瘤標記物,可用于確定胃腸道轉(zhuǎn)移性腺癌和類癌的起源??笴DX-2可用于鑒別肺腺癌和轉(zhuǎn)移性大腸腺癌,而卵巢黏液性癌也可與抗CDX-2呈陽性反應(yīng),從而限制了與轉(zhuǎn)移性大腸腺癌的鑒別能力。
CDX-2 is a caudal-related homeobox transcription factor that is expressed by intestinal epithelial cells. CDX-2 is a useful marker for gastrointestinal carcinoma, and for determining the origin of gastrointestinal metastatic adenocarcinoma and carcinoids. Anti-CDX-2 is used for differentiating lung and metastatic colorectal adenocarcinoma, however mucinous ovarian carcinoma also react positively with Anti-CDX-2, thereby limiting the ability to differentiate from metastatic colorectal adenocarcinoma.
Specifications:
Clone IHC402
Source Mouse Monoclonal
Positive Control Colon
Dilution Range 1:50-1:200
參考文獻References:
Suh E, et al. Mol Cell Biol. 1994; 14:7340-51.
Liu Q, et al. Mod Pathol. 2007; 20:1286–97.
Mazziotta RM, et al. Appl Immunohistochem Mol Morphol. 2005; 13:55-60.
Erickson LA, et al. Endocr Pathol. 2004; 15:247-5.
Kaimaktchiev V, et al. Mod Pathol. 2004; 17:1392-9.
Werling RW, et al. Am J Surg Pathol. 2003; 27:303-10.
Scholl C, et al. J Clin Invest. 2007; 117:1037–48.
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